Despite the extensive commentary on the work of Peter Winch, there has been inadequate recognition of how his Idea of a Social Science discerned the implications of Wittgenstein’s philosophy for confronting issues regarding the nature and interpretation of social phenomena. Winch’s subsequent confrontation with anthropology can be further illuminated by examining one of the most contentious contemporary debates in this field. This case illustrates the paradoxes involved in meta-practices such as philosophy and social science seeking to make descriptive and normative (...) claims about conceptually preconstituted forms of life, and it indicates the limitations of philosophical realism as a social scientific meta-theory. (shrink)

Most land plants associate with mycorrhizal fungi that can connect roots of neighboring plants in common mycelial networks (CMNs). Recent evidence shows that CMNs transfer warning signals of pathogen and aphid attack between plants. However, we do not know how defence‐related signaling via CMNs operates or how ubiquitous it is. Nor do we know what the ecological relevance and fitness consequences are, particularly from the perspective of the mycorrhizal fungus. Here, we focus on the potential fitness benefits for mycorrhizal fungi (...) and outline hypothetical scenarios in which signal transfer via CMNs is modulated in order to acquire the most benefit for the fungus (i.e. acquisition of carbon) for minimal cost. We speculate that the signal may be quantitative and may elicit plant defence responses on different levels depending on the distance the signal is transferred. Finally, we discuss the possibility of practical applications of this phenomenon for crop protection. (shrink)

A distinctive feature of Ludwig Wittgenstein's work after 1930 was his turn to a conception of philosophy as a form of social inquiry, John G. Gunnell argues, and Thomas Kuhn's approach to the philosophy of science exemplified this conception. In this book, Gunnell shows how these philosophers address foundational issues in the social and human sciences, particularly the vision of social inquiry as an interpretive endeavor and the distinctive cognitive and practical relationship between social inquiry and its (...) subject matter. Gunnell speaks directly to philosophers and practitioners of the social and human sciences. He tackles the demarcation between natural and social science; the nature of social phenomena; the concept and method of interpretation; the relationship between language and thought; the problem of knowledge of other minds; and the character of descriptive and normative judgments about practices that are the object of inquiry. Though Wittgenstein and Kuhn are often criticized as initiating a modern descent into relativism, this book shows that the true effect of their work was to undermine the basic assumptions of contemporary social and human science practice. It also problematized the authority of philosophy and other forms of social inquiry to specify the criteria for judging such matters as truth and justice. When Wittgenstein stated that "philosophy leaves everything as it is," he did not mean that philosophy would be left as it was or that philosophy would have no impact on what it studied, but rather that the activity of inquiry did not, simply by virtue of its performance, transform the object of inquiry. (shrink)

Americans have long prided themselves on living in a country that serves as a beacon of democracy to the world, but from the time of the founding they have also engaged in debates over what the criteria for democracy are as they seek to validate their faith in the United States as a democratic regime. In this book John Gunnell shows how the academic discipline of political science has contributed in a major way to this ongoing dialogue, thereby (...) playing a significant role in political education and the formulation of popular conceptions of American democracy. Using the distinctive “internalist” approach he has developed for writing intellectual history, Gunnell traces the dynamics of conceptual change and continuity as American political science evolved from a focus in the nineteenth century on the idea of the state, through the emergence of a pluralist theory of democracy in the 1920s and its transfiguration into liberalism in the mid-1930s, up to the rearticulation of pluralist theory in the 1950s and its resurgence, yet again, in the 1990s. Along the way he explores how political scientists have grappled with a fundamental question about popular sovereignty: Does democracy require a people and a national democratic community, or can the requisites of democracy be achieved through fortuitous social configurations coupled with the design of certain institutional mechanisms? (shrink)

This book is an exploration of the relationship between philosophy and political inquiry. John G. Gunnell is seeking to explain certain dimensions of how philosophy has influenced political science and political theory but also how these latter fields have understood and deployed philosophy. When social scientists and social theorists turn to the work of philosophers for intellectual authority what they extract is often selective and in the service of some prior agenda. The philosophers whose work he discusses have (...) all in various degrees been objects of the conversation of political theory, but close acquaintance with that work is often limited and derivative. Gunnell's goal is to initiate a more genuine "conversation" with certain philosophers and political theorists. (shrink)

The assumed difference and continuing estrangement between political philosophy and political science is a relatively recent development. Both fields sprang from closely entwined concerns about democracy and matters of social and political justice, and today both must still confront their practical as well as cognitive relationship to their subject matter. This issue, however, has receded into the background of these discourses. Ludwig Wittgenstein's vision of philosophy is in effect a vision of social inquiry. His work, when viewed from this perspective, (...) prompts us to reconsider the logical status of various modes of political inquiry: how can these practices, descriptively and normatively, do justice to their subject matter? How can they deal with such foundational issues as the nature of social phenomena, the concepts of representation and interpretation, the problem of knowledge of other minds and what is involved in making explanatory and evaluative judgments about the objects of inquiry? (shrink)

Contemporary literature in cognitive science and the philosophy of mind points to the locus of significant unresolved theoretical and methodological issues in political theory and political science, and particularly to the persistently anomalous status of mental concepts. The manner in which political and social theorists have accessed and deployed this literature, however, has been highly selective and conceptually problematical. The purpose has often been to justify prior agendas, and issues relating to how brain processes are involved in an explanation of (...) political phenomena have not been satisfactorily confronted. Cognitive science is itself a highly contested field with indigenous theoretical difficulties, and it is necessary to sort out and analyze the salient positions in this conversation and to begin, at least tentatively, to assess critically its implications for both social theory and empirical research and to suggest a direction for further investigation. (shrink)

It has been notoriously difficult to link Ludwig Wittgenstein’s work to the agendas of academic political theory. While this is in part due to his style of writing and the absence of an explicit discussion of politics, his commitment to the irreducibility of conventions is difficult to reconcile with the search of many political theorists for both criteria of political essentiality and a basis of cognitive privilege that would underwrite a vision of critical and normative inquiry. Although political theory is (...) characteristically drawn toward the literature of philosophy in search of identity and images of epistemic authority, Wittgenstein’s work subverts the search for the universality of both politics and political inquiry. It is, however, possible to perceive in his work a positive valence for both a vision of political inquiry and criteria of democracy. (shrink)

Using this case, Lavazza and Reichlin (2018) explored the ethical dilemmas associated with decision making in people with Alzheimer’s disease (AD), specifically when their new preferences conflict...

Although social scientists have been devoted to discovering specific realities of social life, many theorists devoted to critical judgment have turned to philosophy in search of universal grounds of truth and reality. They have, however, worried about the problem of relativism. Although Wittgenstein has often been characterized as a relativist, Cora Diamond, inspired by G. E. M Anscombe, argues that his work, despite internal tensions, provides rational grounds for external criticism of social practices. Her argument and her critique of the (...) work of Peter Winch and Ilham Dilman are, however, neither adequately supported by Wittgenstein’s texts nor sufficiently developed on their own terms. (shrink)

Leo Strauss»s Natural Right and History and Eric Voegelin»s New Science of Politics represented both a continuation of the Weimar conversation and a projection into the American context of the issues that defined that conversation. They each chose Max Weber as the pivotal figure in their animadversions regarding historicism, relativism, and the condition of social science, but, as in the case of Weber himself, the underlying issue, which animated the emigres across the ideological spectrum, was the relationship between theory and (...) practice or philosophy and politics. (shrink)

Leo Strauss»s Natural Right and History and Eric Voegelin»s New Science of Politics represented both a continuation of the Weimar conversation and a projection into the American context of the issues that defined that conversation. They each chose Max Weber as the pivotal figure in their animadversions regarding historicism, relativism, and the condition of social science, but, as in the case of Weber himself, the underlying issue, which animated the emigres across the ideological spectrum, was the relationship between theory and (...) practice or philosophy and politics. (shrink)

The issue of the nature of concepts and the problem of understanding conceptual change have become increasingly important in methodological discussions of the study of the history of political thought as well as in substantive research. The treatment of these matters, however, remains inadequate. This is in part a consequence of metatheoretical agendas that have diverted attention away from a theoretical analysis of concepts and apposite issues such as the relationship between mental predicates, words and concepts. But the failure to (...) confront these matters has also been the result of the pervasive emphasis on contextual analysis in historical interpretation. One of the methodological implications of a more thorough theoretical account of concepts is a greater concern with internal history and conceptual genealogy. (shrink)

Hutchinson, Read, and Sharrock have provided an important analysis of the work of Peter Winch. They succeed in rescuing his philosophy from many of the distorting characterizations and categorizations to which it has been subjected, and they provide a fresh account of its relevance for thinking about the theory and practice of social science.

The phenomenological effects of deep brain stimulation (DBS) on the self of the patient remains poorly understood and under described in the literature, despite growing evidence that a significant number of patients experience postoperative neuropsychiatric changes. To address this lack of phenomenological evidence, we conducted in-depth, semistructured interviews with 17 patients with Parkinson's disease who had undergone DBS. Exploring the subjective character specific to patients' experience of being implanted gives empirical and conceptual understanding of the potential phenomenon of DBS-induced self-estrangement. (...) Our study concluded that (1) the more patients preoperatively felt alienated by their illness, the more they experienced postoperative self-estrangement, and (2) the notion of self-estrangement seems to exist in association with certain common qualitative characters, namely, loss of control, which reflects a deteriorative estrangement, and distorted perception of capacities, which reveals a restorative estrangement. These findings indicate that subjective self-reports help us to understand some aspects of the potential phenomenon of DBS-induced self-estrangement. (shrink)

(Statement of Responsibility) by Lewis Carroll ; with illustrations in colors.

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

ObjectiveTo assess distracted attention and performance on a computer task following completion of a sustained attention and acute media multitasking task among adolescents with varying self-reported usual media multitasking.MethodsNinety-six 13- to 17-year-olds played the video game Tetris following completion of a Go/No-go paradigm to measure sustained attention in the presence of distractors, an acute media multitasking, or a passive viewing condition. Adolescents completed the conditions on separate visits in randomized order. Sustained attention was measured within the Go/No-go task by measuring (...) errors of omission. Distracted attention while playing the Tetris task was measured by computing eye tracking measures of attention to irrelevant distractor images that bordered the Tetris game. Participants also self-reported their daily media multitasking.ResultsThe Go/No-go task revealed important qualitative differences in sustained attention among low and high usual media multitaskers. There was a uniform improvement in sustained attention among low usual media multitaskers, demonstrated by a consistent linear decrease in omission errors. Among high usual media multitaskers, there was initially a decrease in sustained attention followed by an increase. Completing the Go/No-go task also statistically significantly reduced distractibility and increased performance while playing Tetris compared to the passive viewing condition, but only among those with low usual media multitasking. There was a non-statistically significant trend that completing the acute media multitask increased subsequent distractibility and performance while playing Tetris among high media multitaskers.ConclusionIn this sample of adolescents, practicing a sustained attention task reduces distractibility and improves task performance among those who have low levels of usual media multitasking. (shrink)